{"id":1334,"date":"2023-07-16T12:41:59","date_gmt":"2023-07-16T03:41:59","guid":{"rendered":"https:\/\/www.elst.okayama-u.ac.jp\/en\/?page_id=1334"},"modified":"2026-01-06T11:31:48","modified_gmt":"2026-01-06T02:31:48","slug":"areas07_biochem","status":"publish","type":"page","link":"https:\/\/www.elst.okayama-u.ac.jp\/en\/education\/mc-chikyu\/areas07_biochem\/","title":{"rendered":"Microbiological Chemistry"},"content":{"rendered":"<h4><span style=\"font-size: 18pt\">Microbiological Chemistry<\/span><\/h4>\n<p><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-69 aligncenter\" src=\"https:\/\/www.elst.okayama-u.ac.jp\/up_load_files\/areas\/areas07_biochem\/theme.png\" alt=\"\" width=\"503\" height=\"202\"><\/p>\n<p>We are conducting research to elucidate the metabolic functions of microorganisms and others so as to apply them to solving environmental problems and producing useful materials. We are pioneering a new field of bioinorganic chemistry that elucidates the interaction between proteins and minerals at the molecular level, such as microorganisms that breathe iron, marine organisms that produce magnetite, and catalytic mechanisms of metalloenzymes. In our laboratory, we are promoting interdisciplinary education and research that incorporates information systems such as machine learning and computational chemistry into general-purpose experimental methods such as genetic engineering, protein engineering, genome editing, and RNA engineering.<\/p>\n<p>&nbsp;<\/p>\n<table class=\"el_table_fix\" style=\"width: 100%\">\n<tbody>\n<tr>\n<th style=\"width: 20%\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium\" src=\"https:\/\/www.elst.okayama-u.ac.jp\/up_load_files\/areas\/areas07_biochem\/TAMURA Takashi.png\" width=\"320\" height=\"408\"><\/th>\n<td style=\"width: 80%\">\n<ul>\n<li style=\"list-style-type: none;font-size: 12px;margin-left: -20px\"><span style=\"font-size: 12pt\">Prof. TAMURA Takashi<\/span><\/li>\n<li style=\"list-style-type: none;font-size: 12px;margin-left: -20px\"><span style=\"font-size: 12pt\">E-mail: tktamura <span style=\"color: #0000ff\">[at]<\/span> okayama-u.ac.jp<\/span><\/li>\n<li style=\"list-style-type: none;font-size: 12px;margin-left: -20px\"><span style=\"font-size: 12pt\">biofuel hydrogen, chemoautotrophic bacteria, biomineralization<\/span><\/li>\n<\/ul>\n<p><span style=\"font-size: 12pt\"><a class=\"el_linkBtn\" href=\"https:\/\/soran.cc.okayama-u.ac.jp\/html\/bfcfb3e889f8b96f74506e4da22f6611_en.html\">Directory of Researchers<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5>Genome modification of sulfate-reducing bacteria and hydrogenase development<\/h5>\n<p><a href=\"https:\/\/www.elst.okayama-u.ac.jp\/up_load_files\/areas\/areas07_biochem\/img1_TAMURA Takashi.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright\" src=\"https:\/\/www.elst.okayama-u.ac.jp\/up_load_files\/areas\/areas07_biochem\/img1_TAMURA Takashi.jpg\" alt=\"\" width=\"266\" height=\"203\"><\/a>[NiFeSe]hydrogenase (Hase) of marine sulfate-reducing bacteria has high oxygen resistance, and it has the potential to invent an energy conversion chip that produces hydrogen from sunlight and seawater. We are developing a technology to purify hydrogenase in one step by modifying the genome of sulfate-reducing bacteria and writing an affinity tag sequence added to the Hase gene.<\/p>\n<p>&nbsp;<\/p>\n<table class=\"el_table_fix\" style=\"width: 100%\">\n<tbody>\n<tr>\n<th style=\"width: 20%\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium\" src=\"https:\/\/www.elst.okayama-u.ac.jp\/up_load_files\/areas\/areas07_biochem\/KANAO Tadayoshi.png\" width=\"320\" height=\"408\"><\/th>\n<td style=\"width: 80%\">\n<ul>\n<li style=\"list-style-type: none;font-size: 12px;margin-left: -20px\"><span style=\"font-size: 12pt\">Prof. KANAO Tadayoshi<\/span><\/li>\n<li style=\"list-style-type: none;font-size: 12px;margin-left: -20px\"><span style=\"font-size: 12pt\">E-mail: tkanao<span style=\"color: #0000ff\"> [at]<\/span> okayama-u.ac.jp<\/span><\/li>\n<li style=\"list-style-type: none;font-size: 12px;margin-left: -20px\"><span style=\"font-size: 12pt\">Applied microbiology, Acidophilic bacteria, Iron- and sulfur-oxidizing bacteria<\/span><\/li>\n<\/ul>\n<p><span style=\"font-size: 12pt\"><a class=\"el_linkBtn\" href=\"https:\/\/soran.cc.okayama-u.ac.jp\/html\/13e4fad2892671dd74506e4da22f6611_en.html\">Directory of Researchers<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5>Research and application of iron-oxidizing bacteria and sulfur-oxidizing bacteria<\/h5>\n<p><a href=\"https:\/\/www.elst.okayama-u.ac.jp\/up_load_files\/areas\/areas07_biochem\/img1_KANAO Tadayoshi.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright\" src=\"https:\/\/www.elst.okayama-u.ac.jp\/up_load_files\/areas\/areas07_biochem\/img1_KANAO Tadayoshi.jpg\" alt=\"\" width=\"266\" height=\"203\"><\/a>Iron\/sulfur-oxidizing bacteria are extreme environment microorganisms that exploit (oxidize) inorganic sulfur compounds such as bivalent iron, sulfur, and highly toxic hydrogen sulfide to assimilate carbon dioxide and grow even in strongly acidic environments with a pH of 3 or less. We are trying to elucidate the mechanisms (metabolism and enzymes) of such extremely special microorganisms that consume iron and sulfur and apply them to the recovery of metal resources and the prevention of heavy metal pollution.<\/p>\n<p>&nbsp;<\/p>\n<table class=\"el_table_fix\" style=\"width: 100%\">\n<tbody>\n<tr>\n<th style=\"width: 20%\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium\" src=\"https:\/\/www.elst.okayama-u.ac.jp\/up_load_files\/areas\/areas07_biochem\/NEMOTO Michiko.jpg\" width=\"320\" height=\"408\"><\/th>\n<td style=\"width: 80%\">\n<ul>\n<li style=\"list-style-type: none;font-size: 12px;margin-left: -20px\"><span style=\"font-size: 12pt\">Prof. NEMOTO Michiko<\/span><\/li>\n<li style=\"list-style-type: none;font-size: 12px;margin-left: -20px\"><span style=\"font-size: 12pt\">E-mail: pyct4x0t <span style=\"color: #0000ff\">[at]<\/span> okayama-u.ac.jp<\/span><\/li>\n<li style=\"list-style-type: none;font-size: 12px;margin-left: -20px\"><span style=\"font-size: 12pt\">Biomineralization, Omics<\/span><\/li>\n<\/ul>\n<p><span style=\"font-size: 12pt\"><a class=\"el_linkBtn\" href=\"https:\/\/www.elst.okayama-u.ac.jp\/\">Directory of Researchers<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5>Biomineralization<\/h5>\n<p><a href=\"https:\/\/www.elst.okayama-u.ac.jp\/up_load_files\/areas\/areas07_biochem\/img1_NEMOTO Michiko.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright\" src=\"https:\/\/www.elst.okayama-u.ac.jp\/up_load_files\/areas\/areas07_biochem\/img1_NEMOTO Michiko.jpg\" alt=\"\" width=\"230\" height=\"146\"><\/a>Biominerals are minerals produced by organisms. They possess various superior material properties due to their structure and composition. Understanding biomineralization could contribute to the development of materials science and nanotechnology. We study biomineralization using omics technologies<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Microbiological Chemistry We are conducting research to elucidate the metabolic functions of microorganisms an [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"parent":150,"menu_order":191,"comment_status":"closed","ping_status":"closed","template":"template-layout_single.php","meta":{"footnotes":""},"class_list":["post-1334","page","type-page","status-publish","hentry"],"aioseo_notices":[],"publishpress_future_action":{"enabled":false,"date":"2026-06-24 22:56:38","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.elst.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/pages\/1334","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.elst.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.elst.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.elst.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.elst.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/comments?post=1334"}],"version-history":[{"count":14,"href":"https:\/\/www.elst.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/pages\/1334\/revisions"}],"predecessor-version":[{"id":3437,"href":"https:\/\/www.elst.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/pages\/1334\/revisions\/3437"}],"up":[{"embeddable":true,"href":"https:\/\/www.elst.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/pages\/150"}],"wp:attachment":[{"href":"https:\/\/www.elst.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/media?parent=1334"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}